What's Inside Our Focus Performance – Spore Life Sciences

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What's Inside Our Focus Performance

What Is It?
This nootropic blend combines the cognitive boosting power of Lion’s Mane with sustained energy from Cordyceps to help you unlock your peak mental performance each day.

What’s In It?
Combines the cognitive boosting power of Lion’s Mane, the sustained energy from Cordyceps, and supported by Ashwagandha and Gingko Biloba to provide increased cognitive enhancement and a mood-stabilizing effect: 

  • Lion’s mane - to help with cognitive function, memory support, and immune function
  • Cordyceps - for all-natural energy production and increase Vo2 Max
  • Ashwagandha - to enhance immune function and mood stabilizing properties
  • Ginkgo Biloba - for cognitive function, mental awareness

What Does It Do?
Focus Performance improves working memory, expanded creativity, and complete support for your brain’s neurological functioning.  On top of all that, we added Lion’s Mane proven neuroprotective benefits.  The formulation offers a rich profile of phytochemicals such as polysaccharides, triterpenoids, amino acids, and polyphenols, as well as additions of vitamins B, B-12, C, and D and minerals will support your overall health.
How Does It Work?
The Focus Performance formula provides an intelligent array of fungal molecules demonstrated in the scientific literature to offer wellness properties.

Polysaccharides in lion’s mane mushrooms can promote neuronal health. [1] An extract of lion’s mane, for example, stimulated the production of nerve growth factor which is involved in regulating and maintaining specific neurons. [2] Mice given lion’s mane mushrooms in their feed (5% w/w) for 7 days had increased nerve growth factor mRNA expression in the hippocampus, a region of the brain instrumental in learning and memory. [3] These properties have been implicated in lion’s mane’s ability to reduce neurodegenerative-induced cell death. [4] In a double-blind study of Japanese men and women aged 50-80 and diagnosed with mild cognitive impairment. [5] The study participants consumed 250 mg of mushroom tablets containing 96% lion’s mane 3 times per day for 16 weeks. Cognitive function scores increased with the timeframe that the participants ingested the mushrooms. 

Traditional uses of cordyceps mushrooms include promotion of health, longevity, and athletic power and endurance. [6] In 1993, Chinese runners who had ingested cordyceps achieved records in several running events, thrusting these mushrooms on the world stage as potential energy enhancers. Thus, cordyceps is used in Spore products to provide a burst of energy. One study demonstrated that, with or without exercising, cordyceps improved exercise endurance by activating skeletal muscle metabolic regulators and increasing antioxidants. [6] A double-blind, placebo-controlled trial also demonstrated these findings in older adults (ages 50-75 years) who ingested 333 mg of dried mushrooms. [7] Aerobic performance improved and the ingestion of the mushrooms pointed to resistance to fatigue. 
The shrub knows as Ashwagandha (Withania somnifera) is a recurrent remedy in Ayurvedic medicine. It is used to promote “youthful vigour” by augmenting muscle strength, endurance, and overall health. [8] The withanolides within ashwagandha bestow intrinsic therapeutic properties including anti-inflammatory, antioxidant, anti-cancer, anti-anxiety, and immune-enhancing effects. [9] Pre-clinical models have shown anti-anxiety, anti-depressive, and neuroprotective properties. [10] A 60-day, double-blind clinical trial demonstrated these effects in humans. [9] Contrasted with the study participants who ingested the placebo, those who consumed ashwagandha daily experienced reductions in cortisol levels, anxiety, and stress. Additionally, testosterone levels increased in male participants. The combination of ashwagandha and maitake extracts demonstrated a synergy for enhancing immune responses to stress via phagocytosis (ingestion of bacteria or other foreign invaders by phagocytes) and increased cytokine levels. [11] While the ashwagandha extract worked well on its own, the beta-glucans within the maitake extract potentiated the immune-enhancing activity.

Ginkgo Biloba (Leaf) is often associated with mental health and cognition. Cognitive decline is associated with neurodegenerative diseases like Alzheimer’s disease and dementia, and gingko biloba extract has shown promise in depressive patients diagnosed with Alzheimer’s disease. [12] An extract of gingko biloba contains flavonoids, terpene lactones, and ginkgolic acids that have provided increased neuroplasticity (the brain's ability to adapt or change), prevented brain edema (swelling), and offered neuroprotection. [13-15] A 2016 meta-analysis of ten reviews of ginkgo biloba extract concluded that “medication with [gingko biloba extracts] showed improvement in cognition and daily activities.” [15] Other reviews have provided similar conclusions. [16] In fact, the Physician’s Desk Reference for Herbal Medicines suggests taking 120 mg of dry extract divided up in multiple doses. [17]
These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
[1] Park YS, Lee HS, Won MH, Lee JH, Lee SY, Lee HY. Effect of an exo-polysaccharide from the culture broth of Hericium erinaceus on enhancement of growth and differentiation of rat adrenal nerve cells. Cytotechnology. 2002;39(3):155-162.
[2] Kawagishi H, Shimada A, Shirai R, Okamoto K, Ojima F, Sakamoto H, et al. Erinacines A, B, and C, strong stimulators of nerve growth factor (NGF)-synthesis, from the mycelia of Hericium erinaceum. Tetrahedron Lett. 1994;35:1569–72.
[3] Mori K, Obara Y, Hirota M, et al. Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells. Biol Pharm Bull. 2008;31(9):1727-1732.
[4] Nagai K, Chiba A, Nishino T, Kubota T, Kawagishi H. Dilinoleoyl-phosphatidylethanolamine from Hericium erinaceum protects against ER stress-dependent Neuro2a cell death via protein kinase C pathway. J Nutr Biochem. 2006;17:525–30.
[5] Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-372.
[6] Kumar R, Negi PS, Singh B, Ilavazhagan G, Bhargava K, Sethy NK. Cordyceps sinensis promotes exercise endurance capacity of rats by activating skeletal muscle metabolic regulators. J Ethnopharmacol. 2011;136(1):260-266.
[7] Chen S, Li Z, Krochmal R, Abrazado M, Kim W, Cooper CB. Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial. J Altern Complement Med. 2010;16(5):585-590.
[8] Kulkarni SK, Dhir A. Withania somnifera: an Indian ginseng. Prog Neuropsychopharmacol Biol Psychiatry 2008;32:1093–105.
[9] Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019;98(37):e17186.
[10] Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S. Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. Phytomedicine. 2000;7(6):463-469.
[11] Vetvicka V, Vetvickova J. Immune enhancing effects of WB365, a novel combination of Ashwagandha (Withania somnifera) and Maitake (Grifola frondosa) extracts. N Am J Med Sci. 2011;3(7):320-324.
[12] DeFeudis FV, Drieu K. Ginkgo biloba extract (EGb 761) and CNS functions: basic studies and clinical applications. Curr Drug Targets. 2000;1(1):25-58.
[13] Tchantchou F, Xu Y, Wu Y, Christen Y, Luo Y. EGb 761 enhances adult hippocampal neurogenesis and phosphorylation of CREB in transgenic mouse model of Alzheimer's disease. FASEB J. 2007;21(10):2400-2408.
[14] Yoshitake T, Yoshitake S, Kehr J. The Ginkgo biloba extract EGb 761(R) and its main constituent flavonoids and ginkgolides increase extracellular dopamine levels in the rat prefrontal cortex. Br J Pharmacol. 2010;159(3):659-668.
[15] Zhang HF, Huang LB, Zhong YB, et al. An overview of systematic reviews of Ginkgo biloba extracts for mild cognitive impairment and dementia. Front Aging Neurosci. 2016;8:276.
[16] Diamond BJ, Shiflett SC, Feiwel N, et al. Ginkgo biloba extract: mechanisms and clinical indications. Arch Phys Med Rehabil. 2000;81(5):668-678.
[17] Physician’s Desk Reference (PDR) for Herbal Medicines. 1st ed. Montvale (NJ): Medical Economics Company; 1998.